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Target
Met repressor
Ligand
BDBM28422
Substrate
n/a
Meas. Tech.
ChEMBL_799627 (CHEMBL1941333)
Kd
4.0±n/a nM
Citation
 Joce, C; White, R; Stockley, PG; Warriner, S; Turnbull, WB; Nelson, A Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues. Bioorg Med Chem Lett 22:278-84 (2011) [PubMed]  Article 
Target
Name:
Met repressor
Synonyms:
Met regulon regulatory protein MetJ
Type:
PROTEIN
Mol. Mass.:
12138.09
Organism:
Escherichia coli
Description:
ChEMBL_799627
Residue:
105
Sequence:
MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
  
Inhibitor
Name:
BDBM28422
Synonyms:
(2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl}(methyl)sulfanylium)butanoate | AdoMet | S-Adenosylmethionine | S-adenosyl-L-[carboxy-14C]methionine | [14COOH]AdoMet
Type:
radiolabeled substrate
Emp. Form.:
C15H22N6O5S
Mol. Mass.:
398.437
SMILES:
C[S+](CC[C@H](N)C([O-])=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Structure:
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