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TargetPapain
LigandBDBM50364003
Substrate/Competitorn/a
Meas. Tech.ChEMBL_804541
IC50>200000±n/a nM
Citation Bhattacharya, AKRana, KC Design, synthesis and biological evaluation of peptidyl-vinylaminophosphonates as novel cysteine protease inhibitors. Bioorg Med Chem19:7129-35 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Papain
Name:Papain
Synonyms:Allergen=Car p 1 | PPI | Papaya proteinase I
Type:Enzyme
Mol. Mass.:38923.01
Organism:Carica papaya
Description:Papain was purchased from Sigma, Germany.
Residue:345
Sequence:
MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50364003
NameBDBM50364003
Synonyms:CHEMBL1950256
TypeSmall organic molecule
Emp. Form.C24H39N2O6P
Mol. Mass.482.55
SMILESCCOP(=O)(CC=C(NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)c1ccccc1)OCC |r,w:6.5|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a