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Target
Carbonic anhydrase 6
Ligand
BDBM50366036
Substrate
n/a
Meas. Tech.
ChEMBL_807333 (CHEMBL1960513)
Ki
8±n/a nM
Citation
 Carta, F; Vullo, D; Maresca, A; Scozzafava, A; Supuran, CT New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. Bioorg Med Chem Lett 22:2182-5 (2012) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 6
Synonyms:
CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
35371.40
Organism:
Homo sapiens (Human)
Description:
P23280
Residue:
308
Sequence:
MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEILDYLRRALN
  
Inhibitor
Name:
BDBM50366036
Synonyms:
CHEMBL1956578
Type:
Small organic molecule
Emp. Form.:
C7H9NO2
Mol. Mass.:
139.1519
SMILES:
Cc1cc(C)o\c(c1)=N\O
Structure:
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