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Target
Plasma alpha-L-fucosidase
Ligand
BDBM50065258
Substrate
n/a
Meas. Tech.
ChEBML_34091
Ki
9.8±n/a nM
Citation
 Andrews, D; Bird, M; Cunningham, M; Ward, P Synthesis of and glycosidase inhibition by -l-homofuconojirimycin Bioorg Med Chem Lett 3:2533-2536 (1993)    Article 
Target
Name:
Plasma alpha-L-fucosidase
Synonyms:
Alpha-L-fucosidase 2 | FUCA2 | FUCO2_HUMAN
Type:
PROTEIN
Mol. Mass.:
54063.48
Organism:
Homo sapiens (Human)
Description:
ChEMBL_34091
Residue:
467
Sequence:
MRPQELPRLAFPLLLLLLLLLPPPPCPAHSATRFDPTWESLDARQLPAWFDQAKFGIFIHWGVFSVPSFGSEWFWWYWQKEKIPKYVEFMKDNYPPSFKYEDFGPLFTAKFFNANQWADIFQASGAKYIVLTSKHHEGFTLWGSEYSWNWNAIDEGPKRDIVKELEVAIRNRTDLRFGLYYSLFEWFHPLFLEDESSSFHKRQFPVSKTLPELYELVNNYQPEVLWSDGDGGAPDQYWNSTGFLAWLYNESPVRGTVVTNDRWGAGSICKHGGFYTCSDRYNPGHLLPHKWENCMTIDKLSWGYRREAGISDYLTIEELVKQLVETVSCGGNLLMNIGPTLDGTISVVFEERLRQMGSWLKVNGEAIYETHTWRSQNDTVTPDVWYTSKPKEKLVYAIFLKWPTSGQLFLGHPKAILGATEVKLLGHGQPLNWISLEQNGIMVELPQLTIHQMPCKWGWALALTNVI
  
Inhibitor
Name:
BDBM50065258
Synonyms:
(2S,3R,4S,5R)-2-Methyl-piperidine-3,4,5-triol | (2S,3R,4S,5R)-2-methylpiperidine-3,4,5-triol | CHEMBL314772 | Fucosidase Inhibitor, 3
Type:
Small organic molecule
Emp. Form.:
C6H13NO3
Mol. Mass.:
147.1723
SMILES:
C[C@@H]1NC[C@@H](O)[C@H](O)[C@@H]1O
Structure:
Search PDB for entries with ligand similarity: