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Target
Adenosylhomocysteinase
Ligand
BDBM50281612
Substrate
n/a
Meas. Tech.
ChEBML_197376
IC50
31±n/a nM
Citation
 Siddiqi, SM; Raissian, M; Schneller, SW; Ikeda, S; Snoeck, R; Andrei, G; Balzarini, J; De Clerq, E ()-7-deazaaristeromycin lacking the hydroxymethyl substituent Bioorg Med Chem Lett 3:663-666 (1993)    Article 
Target
Name:
Adenosylhomocysteinase
Synonyms:
AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN
Type:
PROTEIN
Mol. Mass.:
47714.06
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507791
Residue:
432
Sequence:
MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
  
Inhibitor
Name:
BDBM50281612
Synonyms:
5-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-3-hydroxymethyl-cyclopent-3-ene-1,2-diol | CHEMBL284846
Type:
Small organic molecule
Emp. Form.:
C12H14N4O3
Mol. Mass.:
262.2646
SMILES:
Nc1nccc2n(cnc12)C1C=C(CO)C(O)C1O |t:13|
Structure:
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