Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50288596
Substrate
n/a
Meas. Tech.
ChEMBL_3344 (CHEMBL619044)
Ki
9.6±n/a nM
Citation
 Fancelli, D; Caccia, C; Fornaretto, M; McArthur, R; Severino, D; Vaghi, F; Varasi, M Serotoninergic 5-HT3 and 5-HT4 receptor activities of dihydrobenzofuran carboxylic acid derivatives Bioorg Med Chem Lett 6:263-266 (1996)    Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT-4 | 5-HT4 | 5-HT4L | 5-HT4S | 5-hydroxytryptamine receptor 4 | 5HT4R_RAT | Htr4 | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46117.31
Organism:
RAT
Description:
5-HT4 HTR4 RAT::Q62758
Residue:
406
Sequence:
MDRLDANVSSNEGFGSVEKVVLLTFFAMVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVNAFGAIELVQDIWFYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDVIEKRKFNHNSNSTFCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAQQIQMLQRAGATSESRPQTADQHSTHRMRTETKAAKTLCVIMGCFCFCWAPFFVTNIVDPFIDYTVPEKVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYKRPPILGQTVPCSTTTINGSTHVLRDTVECGGQWESRCHLTATSPLVAAQPVIRRPQDNDLEDSCSLKRSQS
  
Inhibitor
Name:
BDBM50288596
Synonyms:
4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid (3-piperidin-1-yl-propyl)-amide | CHEMBL327798
Type:
Small organic molecule
Emp. Form.:
C17H24ClN3O2
Mol. Mass.:
337.844
SMILES:
Nc1c2CCOc2c(cc1Cl)C(=O)NCCCN1CCCCC1
Structure:
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