Reaction Details Report a problem with these data
Target
Cholecystokinin receptor type A
Ligand
BDBM50291424
Substrate
n/a
Meas. Tech.
ChEBML_50195
IC50
3846±n/a nM
Citation
 Herrero, S; Suarez-Gea, M; Gonzalez-Muniz, R; Garcia-Lopez, M; Herranz, R; Ballaz, S; Barber, A; Fortuno, A; Del Rio, J Pseudopeptide CCK-4 analogues incorporating the [CH(CN)NH] peptide bond surrogate Bioorg Med Chem Lett 7:855-860 (1997)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50291424
Synonyms:
(S)-3-{(S)-2-[(1R,2S)-2-Benzyloxycarbonylamino-1-cyano-3-(1H-indol-3-yl)-propylamino]-hexanoylamino}-N-((S)-1-carbamoyl-2-phenyl-ethyl)-succinamic acid | CHEMBL168435
Type:
Small organic molecule
Emp. Form.:
C39H45N7O7
Mol. Mass.:
723.8173
SMILES:
CCCC[C@H](N[C@@H](C#N)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure:
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