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Target
M-phase inducer phosphatase 1
Ligand
BDBM50093973
Substrate
n/a
Meas. Tech.
ChEBML_49010
IC50
>300000±n/a nM
Citation
 Takahashi, M; Dodo, K; Sugimoto, Y; Aoyagi, Y; Yamada, Y; Hashimoto, Y; Shirai, R Synthesis of the novel analogues of dysidiolide and their structure-activity relationship. Bioorg Med Chem Lett 10:2571-4 (2001) [PubMed]  Article 
Target
Name:
M-phase inducer phosphatase 1
Synonyms:
CDC25A | Dual specificity phosphatase (Cdc25A) | Dual specificity phosphatase Cdc25A | M-phase inducer phosphatase 1 | MPIP1_HUMAN | phosphatase Cdc25
Type:
Protein
Mol. Mass.:
59090.18
Organism:
Homo sapiens (Human)
Description:
P30304
Residue:
524
Sequence:
MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
  
Inhibitor
Name:
BDBM50093973
Synonyms:
5-Hydroxy-4-[1-hydroxy-2-(1-methyl-cyclohexyl)-ethyl]-5H-furan-2-one | CHEMBL86451
Type:
Small organic molecule
Emp. Form.:
C13H20O4
Mol. Mass.:
240.2955
SMILES:
CC1(CC(O)C2=CC(=O)OC2O)CCCCC1 |t:5|
Structure:
Search PDB for entries with ligand similarity: