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Target
Delta-type opioid receptor
Ligand
BDBM50101295
Substrate
n/a
Meas. Tech.
ChEBML_147175
Ki
12±n/a nM
Citation
 Nortey, SO; Baxter, EW; Codd, EE; Zhang, SP; Reitz, AB Piperazinyl benzamidines: synthesis and affinity for the delta opioid receptor. Bioorg Med Chem Lett 11:1741-3 (2001) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | OPRD_RAT | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Opioid receptors; mu & delta | Oprd1 | Ror-a | Voltage-gated potassium channel
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40465.04
Organism:
Rattus norvegicus (rat)
Description:
Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:
372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50101295
Synonyms:
4-{(4-Benzyl-piperazin-1-yl)-[(Z)-2-chloro-phenylimino]-methyl}-N,N-diethyl-benzamide | CHEMBL297498
Type:
Small organic molecule
Emp. Form.:
C29H33ClN4O
Mol. Mass.:
489.052
SMILES:
CCN(CC)C(=O)c1ccc(cc1)C(=N\c1ccccc1Cl)\N1CCN(Cc2ccccc2)CC1
Structure:
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