Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBeta-glucosidase
LigandBDBM50104296
Substrate/Competitorn/a
Meas. Tech.ChEMBL_37428
IC50 70000±n/a nM
Citation Popowycz, FGerber-Lemaire, SDemange, RRodriguez-García, EAsenjo, ATRobina, IVogel, P Derivatives of (2R,3R,4S)-2-aminomethylpyrrolidine-3,4-diol are selective alpha-mannosidase inhibitors. Bioorg Med Chem Lett11:2489-93 (2001) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Beta-glucosidase
Name:Beta-glucosidase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:60428.49
Organism:Prunus avium
Description:ChEMBL_37428
Residue:531
Sequence:
LLLLGFALANTNAARTDPPVVCATLNRTNFDTLFPGFTFGTATASYQLEGAANIDGRGPS
IWDAFTHNHPEKITDGSNGDVAIDQYHRYKEDVAIMKDMGLDAYRFSISWSRLLPNGTLS
GGINKKGIEYYNNLTNELIRNGIEPLVTLFHWDVPQALEEEYGGVLSPRIVYDFKAYAEL
CYKEFGDRVKHWTTLNEPYTISNHGYTIGIHAPGRCSSWYDPTCLGGDSGTEPYLVTHNL
LLAHAAAVKLYREKYQASQEGVIGITVVSHWFEPASESQKDINASVRALDFMYGWFMDPL
TRGDYPQSMRSLVKERLPNFTEEQSKSLIGSYDYIGVNYYSARYASAYPEDYSIPTPPSY
LTDAYVNVTTELNGVPIGPQAASDWLYVYPKGLYDLVLYTKNKYNDPIMYITENGMDEFN
NPKISLEQALNDSNRIDYCYRHLCYLQEAIIEGANVQGYFAWSLLDNFEWSEGYTVRFGI
NYVDYDNGLKRHSKLSTHWFKNFLKRSSISKEKIRRCGNNNARARKFVYRI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50104296
NameBDBM50104296
Synonyms:2-(2,2-Dihydroxy-ethyl)-pyrrolidine-3,4-diol | CHEMBL83278
TypeSmall organic molecule
Emp. Form.C6H13NO4
Mol. Mass.163.1717
SMILESOC(O)CC1NCC(O)C1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a