Reaction Details Report a problem with these data
Target
Protein Tat
Ligand
BDBM50097335
Substrate
n/a
Meas. Tech.
ChEBML_209906
IC50
600±n/a nM
Citation
 Hamasaki, K; Ueno, A Aminoglycoside antibiotics, neamine and its derivatives as potent inhibitors for the RNA-protein interactions derived from HIV-1 activators. Bioorg Med Chem Lett 11:591-4 (2001) [PubMed]  Article 
Target
Name:
Protein Tat
Synonyms:
Human immunodeficiency virus type 1 Tat protein | Protein Tat | TAT_HV112 | Transactivating regulatory protein | tat
Type:
PROTEIN
Mol. Mass.:
9771.75
Organism:
Human immunodeficiency virus type 1 (isolate PCV12 group M subtype B)(HIV-1)
Description:
ChEMBL_199318
Residue:
86
Sequence:
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQGSQTHQVSLSKQPTSQSRGDPTGPKE
  
Inhibitor
Name:
BDBM50097335
Synonyms:
2-Amino-5-guanidino-pentanoic acid [(4R,5S,6S)-5-amino-6-((2R,3R,4R)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-3,4-dihydroxy-tetrahydro-pyran-2-ylmethyl]-amide | CHEMBL155256
Type:
Small organic molecule
Emp. Form.:
C18H38N8O7
Mol. Mass.:
478.5437
SMILES:
NC(CCCNC(N)=N)C(=O)NCC1OC(OC2C(N)CC(N)C(O)C2O)C(N)C(O)C1O
Structure:
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