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TargetDipeptidyl peptidase 2 (DPP II)
LigandBDBM50118939
Substrate/Competitorn/a
Meas. Tech.ChEBML_53193
IC50 79000±n/a nM
Citation Senten, KVan der Veken, PBal, GDe Meester, ILambeir, AMScharpé, SBauvois, BHaemers, AAugustyns, K Development of potent and selective dipeptidyl peptidase II inhibitors. Bioorg Med Chem Lett12:2825-8 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dipeptidyl peptidase 2 (DPP II)
Name:Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4)
Synonyms:DAP II | Dipeptidyl aminopeptidase II | Dipeptidyl peptidase 2 (DPP2) | Dipeptidyl peptidase II (DDP-II) | Dipeptidyl peptidase II (DPP II) | carboxytripeptidase | dipeptidyl arylamidase II | dipeptidyl(amino)peptidase II | dipeptidylarylamidase
Type:Protein
Mol. Mass.:54339.29
Organism:Homo sapiens (Human)
Description:Q9UHL4
Residue:492
Sequence:
MGSAPWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVS
DRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQS
TQRGHTELLTVEQALADFAELLRALRRDLGAQDAPAIAFGGSYGGMLSAYLRMKYPHLVA
GALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKDLFLQGAYDTVR
WEFGTCQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPANPVKVGCDRLLSEA
QRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFA
SNNVTDMFPDLPFTDELRQRYCLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPW
AGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQ
QPALRGGPRLSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50118939
NameBDBM50118939
Synonyms:2-Amino-3-phenyl-1-pyrrolidin-1-yl-propan-1-one | CHEMBL93931
TypeSmall organic molecule
Emp. Form.C13H18N2O
Mol. Mass.218.2948
SMILESNC(Cc1ccccc1)C(=O)N1CCCC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a