Reaction Details Report a problem with these data
Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50111175
Substrate
n/a
Meas. Tech.
ChEBML_105842
Ki
2900±n/a nM
Citation
 Mutulis, F; Mutule, I; Wikberg, JE N-alkylaminoacids and their derivatives interact with melanocortin receptors. Bioorg Med Chem Lett 12:1039-42 (2002) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50111175
Synonyms:
(2S)-5-[(E)-[amino(azaniumyl)methylidene]amino]-N-(naphthalen-2-yl)-2-[(naphthalen-2-ylmethyl)amino]pentanamide | MK-56 | N-Alkylaminoacid derivative
Type:
Small organic molecule
Emp. Form.:
C27H30N5O
Mol. Mass.:
440.5595
SMILES:
[NH3+]C(=N)NCCC[C@H](NCc1ccc2ccccc2c1)C(=O)Nc1ccc2ccccc2c1
Structure:
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