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Target
Beta-galactoside alpha-2,6-sialyltransferase 1
Ligand
BDBM50366833
Substrate
n/a
Meas. Tech.
ChEMBL_216152 (CHEMBL817949)
Ki
730000±n/a nM
Citation
 Whalen, LJ; McEvoy, KA; Halcomb, RL Synthesis and evaluation of phosphoramidate amino acid-based inhibitors of sialyltransferases. Bioorg Med Chem Lett 13:301-4 (2002) [PubMed]  Article 
Target
Name:
Beta-galactoside alpha-2,6-sialyltransferase 1
Synonyms:
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase | SIAT1_RAT | Siat1 | St6gal1
Type:
PROTEIN
Mol. Mass.:
46743.36
Organism:
Rattus norvegicus
Description:
ChEMBL_216152
Residue:
403
Sequence:
MIHTNLKKKFSLFILVFLLFAVICVWKKGSDYEALTLQAKEFQMPKSQEKVAMGSASQVVFSNSKQDPKEDIPILSYHRVTAKVKPQPSFQVWDKDSTYSKLNPRLLKIWRNYLNMNKYKVSYKGPGPGVKFSVEALRCHLRDHVNVSMIEATDFPFNTTEWEGYLPKENFRTKVGPWQRCAVVSSAGSLKNSQLGREIDNHDAVLRFNGAPTDNFQQDVGSKTTIRLMNSQLVTTEKRFLKDSLYTEGILIVWDPSVYHADIPKWYQKPDYNFFETYKSYRRLNPSQPFYILKPQMPWELWDIIQEISADLIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYHQKFFDSACTMGAYDPLLFEKNMVKHLNEGTDEDIYLFGKATLSGFRNIRC
  
Inhibitor
Name:
BDBM50366833
Synonyms:
CHEMBL608928
Type:
Small organic molecule
Emp. Form.:
C20H24N5O9P
Mol. Mass.:
509.4064
SMILES:
Nc1ccn(C2O[C@H](COP(O)(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(O)=O)[C@@H](O)[C@H]2O)c(=O)n1 |r|
Structure:
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