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Target
Sphingosine 1-phosphate receptor 1
Ligand
BDBM50133427
Substrate
n/a
Meas. Tech.
ChEMBL_201311 (CHEMBL805799)
EC50
598.40±n/a nM
Citation
 Clemens, JJ; Davis, MD; Lynch, KR; Macdonald, TL Synthesis of para-alkyl aryl amide analogues of sphingosine-1-phosphate: discovery of potent S1P receptor agonists. Bioorg Med Chem Lett 13:3401-4 (2003) [PubMed]  Article 
Target
Name:
Sphingosine 1-phosphate receptor 1
Synonyms:
CHEDG1 | EDG1 | Endothelial differentiation G-protein coupled receptor 1 | S1P receptor | S1P1 | S1PR1 | S1PR1_HUMAN | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:
Enzyme
Mol. Mass.:
42836.02
Organism:
Homo sapiens (Human)
Description:
P21453
Residue:
382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSHPQKDEGDNPETIMSSGNVNSSS
  
Inhibitor
Name:
BDBM50133427
Synonyms:
CHEMBL324358 | Phosphoric acid mono-((S)-2-amino-2-dodecylcarbamoyl-ethyl) ester; TFA
Type:
Small organic molecule
Emp. Form.:
C15H33N2O5P
Mol. Mass.:
352.4067
SMILES:
CCCCCCCCCCCCNC(=O)[C@@H](N)COP(O)(O)=O
Structure:
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