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Target
Mu-type opioid receptor
Ligand
BDBM50123274
Substrate
n/a
Meas. Tech.
ChEBML_145141
Ki
6.1±n/a nM
Citation
 Ananthan, S; Kezar, HS; Saini, SK; Khare, NK; Davis, P; Dersch, CM; Porreca, F; Rothman, RB Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans. Bioorg Med Chem Lett 13:529-32 (2003) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50123274
Synonyms:
6-amino(imino)methylamino-19-cyclopropylmethyl-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol; ditrifluoracetic acid | CHEMBL348011
Type:
Small organic molecule
Emp. Form.:
C24H27N5O3
Mol. Mass.:
433.5029
SMILES:
[#7]\[#6](-[#7])=[#7]/c1cnc2-[#6@@H]3-[#8]-c4c5c(-[#6]-[#6@H]6-[#7](-[#6]-[#6]-7-[#6]-[#6]-7)-[#6]-[#6][C@@]35[C@@]6([#8])[#6]-c2c1)ccc4-[#8]
Structure:
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