Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetCoagulation factor X/antithrombin III
LigandBDBM50124864
Substrate/Competitorn/a
Meas. Tech.ChEBML_69660
Kd 10700±n/a nM
Citation Gunnarsson, GTDesai, UR Exploring new non-sugar sulfated molecules as activators of antithrombin. Bioorg Med Chem Lett13:679-83 (2003) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Coagulation factor X/antithrombin III
Name:Coagulation factor X/antithrombin III
Synonyms:Activated coagulation factor X (FXa) | Activated factor Xa heavy chain | Coagulation factor X precursor | Coagulation factor Xa | Factor X heavy chain | Factor X light chain | Factor Xa | Stuart factor | Stuart-Prower factor
Type:Enzyme
Mol. Mass.:54726.60
Organism:Homo sapiens (human)
Description:n/a
Residue:488
Sequence:
MGRPLHLVLLSASLAGLLLLGESLFIRREQANNILARVTRANSFLEEMKKGHLERECMEE
TCSYEEAREVFEDSDKTNEFWNKYKDGDQCETSPCQNQGKCKDGLGEYTCTCLEGFEGKN
CELFTRKLCSLDNGDCDQFCHEEQNSVVCSCARGYTLADNGKACIPTGPYPCGKQTLERR
KRSVAQATSSSGEAPDSITWKPYDAADLDPTENPFDLLDFNQTQPERGDNNLTRIVGGQE
CKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGE
AVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGI
VSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSG
GPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTRGLPKAKSHAPE
VITSSPLK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50124864
NameBDBM50124864
Synonyms:(2S,3S)-2-[3,4-bis(sulfonatooxy)phenyl]-3,5-bis(sulfonatooxy)-3,4-dihydro-2H-chromen-7-yl sulfate
TypeSmall organic molecule
Emp. Form.C15H9O21S5
Mol. Mass.685.547
SMILES[O-]S(=O)(=O)O[C@H]1Cc2c(OS([O-])(=O)=O)cc(OS([O-])(=O)=O)cc2O[C@H]1c1ccc(OS([O-])(=O)=O)c(OS([O-])(=O)=O)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a