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TargetAdenosine Receptors A2a (A2a)
LigandBDBM50124120
Substrate/Competitorn/a
Meas. Tech.ChEBML_30018
Ki>10000±n/a nM
Citation Lim, MHKim, HOMoon, HRLee, SJChun, MWGao, ZGMelman, NJacobson, KAKim, JHJeong, LS Design, synthesis and binding affinity of 3'-fluoro analogues of Cl-IB-MECA as adenosine A3 receptor ligands. Bioorg Med Chem Lett13:817-20 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine Receptors A2a (A2a)
Name:Adenosine receptor A2a and A3
Synonyms:ADENOSINE A2a | Adenosine A2a receptor (A2a) | Adenosine receptors A2a | Rat striatal adenosine A2a receptor
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:45015.65
Organism:Rattus norvegicus (rat)
Description:Rat A2A receptors expressed in CHO cells.
Residue:410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
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  Blast E-value cutoff:
BDBM50124120
NameBDBM50124120
Synonyms:2-[2-chloro-6-(methylamino)-9H-purin-9-yl]-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol | CHEMBL168843
TypeSmall organic molecule
Emp. Form.C11H13ClFN5O3
Mol. Mass.317.704
SMILESCNc1nc(Cl)nc2n(cnc12)C1OC(CO)C(F)C1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a