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TargetPhosphatidylcholine-retinol O-acyltransferase
LigandBDBM8580
Substrate/Competitorn/a
Meas. Tech.ChEMBL_96915
IC50 38600±n/a nM
Citation Ryu, DHTan, CHRando, RR Synthesis of (+),(-)-neamine and their positional isomers as potential antibiotics. Bioorg Med Chem Lett13:901-3 (2003) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Phosphatidylcholine-retinol O-acyltransferase
Name:Phosphatidylcholine-retinol O-acyltransferase
Synonyms:Lecithin retinol acyltransferase | Phosphatidylcholine--retinol O-acyltransferase
Type:PROTEIN
Mol. Mass.:25705.63
Organism:Homo sapiens (Human)
Description:ChEMBL_96915
Residue:230
Sequence:
MKNPMLEVVSLLLEKLLLISNFTLFSSGAAGEDKGRNSFYETSSFHRGDVLEVPRTHLTH
YGIYLGDNRVAHMMPDILLALTDDMGRTQKVVSNKRLILGVIVKVASIRVDTVEDFAYGA
NILVNHLDESLQKKALLNEEVARRAEKLLGFTPYSLLWNNCEHFVTYCRYGTPISPQSDK
FCETVKIIIRDQRSVLASAVLGLASIVCTGLVSYTTLPAIFIPFFLWMAG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM8580
NameBDBM8580
Synonyms:(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl]oxy}oxane-3,4-diol | Neamine
TypeSmall organic molecule
Emp. Form.C12H26N4O6
Mol. Mass.322.358
SMILESNC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O |r|
Structure
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n/a