Reaction Details Report a problem with these data
Target
Adenylate kinase 2, mitochondrial
Ligand
BDBM50367066
Substrate
n/a
Meas. Tech.
ChEBML_32046
Ki
1800000±n/a nM
Citation
 Hampton, A; Picker, D; Nealy, KA; Maeda, M Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 4. Interactions of adenosine 5'-triphosphate derivatives with adenylate kinases from Escherichia coli and rat tissues. J Med Chem 25:382-6 (1982) [PubMed]  Article 
Target
Name:
Adenylate kinase 2, mitochondrial
Synonyms:
2.7.4.3 | AK 2 | ATP-AMP transphosphorylase 2 | ATP:AMP phosphotransferase | Adenylate kinase 2 | Adenylate kinase 2, mitochondrial | Adenylate monophosphate kinase | Ak2 | KAD2_RAT
Type:
n/a
Mol. Mass.:
26380.21
Organism:
Rattus norvegicus
Description:
n/a
Residue:
239
Sequence:
MAPNALAPEPEHPEGIRAVLLGPPGAGKGTQAPKLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPSCKNGFLLDGFPRTVKQAEMLDDLMDKRKEKLDSVIEFSIQDSLLIRRITGRLIHPKSGRSYHEEFNPPKEAMKDDITGEPLIRRSDDNEKALKTRLEAYHTQTTPLVEYYRKRGIHCAIDASQTPDVVFASILAAFSKATCKDLVMFV
  
Inhibitor
Name:
BDBM50367066
Synonyms:
CHEMBL3350509 | CHEMBL610373
Type:
Small organic molecule
Emp. Form.:
C27H47IN7O15P3
Mol. Mass.:
929.5257
SMILES:
CN(CCCCCCN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O)C(=O)CCCCCCNC(=O)CI |r|
Structure:
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