Reaction Details Report a problem with these data
Target
Adenylate kinase 2, mitochondrial
Ligand
BDBM50367070
Substrate
n/a
Meas. Tech.
ChEBML_32036
Ki
7300000±n/a nM
Citation
 Hampton, A; Picker, D; Nealy, KA; Maeda, M Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 4. Interactions of adenosine 5'-triphosphate derivatives with adenylate kinases from Escherichia coli and rat tissues. J Med Chem 25:382-6 (1982) [PubMed]  Article 
Target
Name:
Adenylate kinase 2, mitochondrial
Synonyms:
ADK2 | AK 2 | AK2 | ATP-AMP transphosphorylase 2 | Adenylate kinase 2 | Adenylate kinase 2, mitochondrial | KAD2_HUMAN
Type:
PROTEIN
Mol. Mass.:
26480.98
Organism:
Homo sapiens (Human)
Description:
ChEMBL_32036
Residue:
239
Sequence:
MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI
  
Inhibitor
Name:
BDBM50367070
Synonyms:
CHEMBL609238
Type:
Small organic molecule
Emp. Form.:
C16H30N7O13P3
Mol. Mass.:
621.3698
SMILES:
NCCCCCCNc1nc2c(N)ncnc2n1C1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |r|
Structure:
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