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Target
Thymidine kinase 2, mitochondrial (Predicted)
Ligand
BDBM50132297
Substrate
n/a
Meas. Tech.
ChEBML_123826
Ki
4600000±n/a nM
Citation
 Hampton, A; Chawla, RR; Kappler, F Species- or isozyme-specific enzyme inhibitors. 5. Differential effects of thymidine substituents on affinity for rat thymidine kinase isozymes. J Med Chem 25:644-9 (1982) [PubMed]  Article 
Target
Name:
Thymidine kinase 2, mitochondrial (Predicted)
Synonyms:
Thymidine kinase 2
Type:
PROTEIN
Mol. Mass.:
31092.55
Organism:
Rattus norvegicus
Description:
ChEMBL_123826
Residue:
270
Sequence:
MLLRSLRSWAARSLRSMGPGSSGSPGSLDSGAGPLWAPRRACPPDKDREKDKEKKAVVCIEGNIASGKTTCLEFFSNTTDVEVLMEPVLKWRNVHGHNPLSLMYHNASRWGLTLQTYVQLTMLDQHTRPQMSPVRLMERSIYSARYIFVENLYRSGKMPEVDYAILSEWFDWIIKNIDVSVDLIVYLRTTPEICYQRLKMRCREEEKVIPVEYLSAIHHLYEEWLVTGSLFPAAAPVLVIEADHNLEKMLELFEQNRARILTPENWKHGP
  
Inhibitor
Name:
BDBM50132297
Synonyms:
1-((2R,4S,5R)-5-(aminomethyl)-4-hydroxy-tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | 1-((2R,5R)-5-Aminomethyl-4-hydroxy-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione | 5'-AMINO-5'-DEOXYTHYMIDINE | CHEMBL319447
Type:
Small organic molecule
Emp. Form.:
C10H15N3O4
Mol. Mass.:
241.2438
SMILES:
Cc1cn([C@H]2C[C@H](O)[C@@H](CN)O2)c(=O)[nH]c1=O |r|
Structure:
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