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Target
Thymidine kinase, cytosolic
Ligand
BDBM50207303
Substrate
n/a
Meas. Tech.
ChEBML_208005
Ki
5060±n/a nM
Citation
 Efange, SM; Alessi, EM; Shih, HC; Cheng, YC; Bardos, TJ Synthesis and biological activities of 2-pyrimidinone nucleosides. 2. 5-Halo-2-pyrimidinone 2'-deoxyribonucleosides. J Med Chem 28:904-10 (1985) [PubMed]  Article 
Target
Name:
Thymidine kinase, cytosolic
Synonyms:
KITH_HUMAN | TK1
Type:
PROTEIN
Mol. Mass.:
25476.50
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1333884
Residue:
234
Sequence:
MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTRYSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVIVAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADKYHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
  
Inhibitor
Name:
BDBM50207303
Synonyms:
5-BROMO-2'-DEOXY URIDINE | 5-bromo-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | Bromodeoxyuridine | CHEMBL222280 | cid_6035
Type:
Small organic molecule
Emp. Form.:
C9H11BrN2O5
Mol. Mass.:
307.098
SMILES:
OC[C@H]1O[C@H](C[C@@H]1O)n1cc(Br)c(=O)[nH]c1=O |r|
Structure:
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