Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50009552
Substrate
n/a
Meas. Tech.
ChEBML_28964
IC50
2.5±n/a nM
Citation
 Kwatra, MM; Leung, E; Hosey, MM; Green, RD N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors. J Med Chem 30:954-6 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_CHICK | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36337.19
Organism:
Chick
Description:
ADENOSINE A1 ADORA1 Chick::P49892
Residue:
324
Sequence:
MAQSVTAFQAAYISIEVLIALVSVPGNILVIWAVKMNQALRDATFCFIVSLAVADVAVGALVIPLAIIINIGPQTEFYSCLMMACPVLILTESSILALLAIAVDRYLRVKIPVRYKSVVTPRRAAVAIACCWIVSFLVGLTPMFGWNNLNKVLGTRDLNVSHSEFVIKCQFETVISMEYMVYFNFFVWVLPPLLLMLLIYLEVFNLIRTQLNKKVSSSSNDPQKYYGKELKIAKSLALVLFLFALSWLPLHILNCITLFCPSCKTPHILTYIAIFLTHGNSAMNPIVYAFRIKKFRTAFLQIWNQYFCCKTNKSSSSSTAETVN
  
Inhibitor
Name:
BDBM50009552
Synonyms:
2-[6-Amino-2-(2-morpholin-4-yl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol | CHA | CHEMBL45891 | N6-Cyclohexylado (CHA)
Type:
Small organic molecule
Emp. Form.:
C16H23N5O4
Mol. Mass.:
349.3849
SMILES:
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCCC3)ncnc12 |r|
Structure:
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