Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50367273
Substrate
n/a
Meas. Tech.
ChEBML_28964
IC50
8.5±n/a nM
Citation
 Kwatra, MM; Leung, E; Hosey, MM; Green, RD N6-phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptors. J Med Chem 30:954-6 (1987) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_CHICK | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36337.19
Organism:
Chick
Description:
ADENOSINE A1 ADORA1 Chick::P49892
Residue:
324
Sequence:
MAQSVTAFQAAYISIEVLIALVSVPGNILVIWAVKMNQALRDATFCFIVSLAVADVAVGALVIPLAIIINIGPQTEFYSCLMMACPVLILTESSILALLAIAVDRYLRVKIPVRYKSVVTPRRAAVAIACCWIVSFLVGLTPMFGWNNLNKVLGTRDLNVSHSEFVIKCQFETVISMEYMVYFNFFVWVLPPLLLMLLIYLEVFNLIRTQLNKKVSSSSNDPQKYYGKELKIAKSLALVLFLFALSWLPLHILNCITLFCPSCKTPHILTYIAIFLTHGNSAMNPIVYAFRIKKFRTAFLQIWNQYFCCKTNKSSSSSTAETVN
  
Inhibitor
Name:
BDBM50367273
Synonyms:
CHEMBL605042
Type:
Small organic molecule
Emp. Form.:
C17H19N5O4
Mol. Mass.:
357.3639
SMILES:
Cc1ccc(Nc2ncnc3n(cnc23)C2O[C@H](CO)[C@@H](O)[C@H]2O)cc1 |r|
Structure:
Search PDB for entries with ligand similarity: