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Target
Dipeptidase 1
Ligand
BDBM50024004
Substrate
n/a
Meas. Tech.
ChEBML_216035
Ki
910±n/a nM
Citation
 Graham, DW; Ashton, WT; Barash, L; Brown, JE; Brown, RD; Canning, LF; Chen, A; Springer, JP; Rogers, EF Inhibition of the mammalian beta-lactamase renal dipeptidase (dehydropeptidase-I) by (Z)-2-(acylamino)-3-substituted-propenoic acids. J Med Chem 30:1074-90 (1987) [PubMed]  Article 
Target
Name:
Dipeptidase 1
Synonyms:
DPEP1 | DPEP1_PIG | Dipeptidase 1 | Leukotriene D4 Alpha | Microsomal dipeptidase | RDP | Renal dipeptidase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44697.32
Organism:
GUINEA PIG
Description:
Leukotriene D4 Alpha 0 GUINEA PIG::P22412
Residue:
409
Sequence:
MWTSWWLWPLVAVCAADQFRDLAVRIMQDTPVIDGHNDLPWQLLNLFNNQLQDPGANLSSLAHTHTNIPKLKAGFVGGQFWSAYVPCDTQNRDAVKRTLEQIDVIQRMCQAYPETFACVTSSTGIRQAFREGKVASLVGVEGGHSIDSSLGVLRALYHLGMRYMTLTHSCNTPWADNWLVDTGDDKAQSQGLSHFGQSVVKEMNRLGVMIDLAHVSVATMRAALKLSQAPVIFSHSSAYSLCPHRRNVPDDVLQLVKETGSLVMVNFYNDYVSCSAKANLSQVADHLDHIKKVAGAAAVGFGGDYDGVSRVPSGLEDVSKYPDLVAELLRRQWTEAEVRGALADNLLRVFEAVEQASNHAQVPGEEPIPLGQLEASCRTNYGYSAAPSLHLPPGSLLASLVPLLLLSLP
  
Inhibitor
Name:
BDBM50024004
Synonyms:
CHEMBL3559622 | {7-Carboxy-7-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-6-enyl}-(2-hydroxy-ethyl)-dimethyl-ammonium
Type:
Small organic molecule
Emp. Form.:
C18H32N2O4
Mol. Mass.:
340.4577
SMILES:
CC1(C)CC1C(=O)N\C(=C/CCCCC[N+](C)(C)CCO)C([O-])=O
Structure:
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