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Target
Beta-1 adrenergic receptor
Ligand
BDBM50019057
Substrate
n/a
Meas. Tech.
ChEMBL_39181 (CHEMBL654478)
EC50
>1500±n/a nM
Citation
 Adejare, A; Gusovsky, F; Padgett, W; Creveling, CR; Daly, JW; Kirk, KL Syntheses and adrenergic activities of ring-fluorinated epinephrines. J Med Chem 31:1972-7 (1988) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50019057
Synonyms:
(+/-)4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol | 4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol | 4-Fluoro-5-(1-hydroxy-2-methylamino-ethyl)-benzene-1,2-diol(6-FEPI) | CHEMBL42359
Type:
Small organic molecule
Emp. Form.:
C9H12FNO3
Mol. Mass.:
201.1949
SMILES:
CNCC(O)c1cc(O)c(O)cc1F
Structure:
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