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Target
Adenosine receptor A1
Ligand
BDBM50023392
Substrate
n/a
Meas. Tech.
ChEMBL_29101 (CHEMBL857609)
Kd
32±n/a nM
Citation
 Linden, J; Patel, A; Earl, CQ; Craig, RH; Daluge, SM 125I-labeled 8-phenylxanthine derivatives: antagonist radioligands for adenosine A1 receptors. J Med Chem 31:745-51 (1988) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50023392
Synonyms:
CHEMBL349519 | {4-[3-(4-Amino-benzyl)-2,6-dioxo-1-propyl-2,3,6,9-tetrahydro-1H-purin-8-yl]-phenoxy}-acetic acid
Type:
Small organic molecule
Emp. Form.:
C23H23N5O5
Mol. Mass.:
449.4592
SMILES:
CCCn1c(=O)n(Cc2ccc(N)cc2)c2nc([nH]c2c1=O)-c1ccc(OCC(O)=O)cc1
Structure:
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