Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50452573
Substrate
n/a
Meas. Tech.
ChEBML_29460
Ki
0.240000±n/a nM
Citation
 Trivedi, BK; Bridges, AJ; Patt, WC; Priebe, SR; Bruns, RF N6-bicycloalkyladenosines with unusually high potency and selectivity for the adenosine A1 receptor. J Med Chem 32:8-11 (1989) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50452573
Synonyms:
CHEMBL3038260
Type:
Small organic molecule
Emp. Form.:
C17H22ClN5O3
Mol. Mass.:
379.841
SMILES:
[H][C@]12CCC(C1)[C@]([H])(C2)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CCl)[C@@H](O)[C@H]1O |r,THB:9:6:5:3.2|
Structure:
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