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Reaction Details
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TargetAdenosine receptor A1
LigandBDBM50267577
Substrate/Competitorn/a
Meas. Tech.ChEBML_29460
Ki 0.420000±n/a nM
Citation Trivedi, BKBridges, AJPatt, WCPriebe, SRBruns, RF N6-bicycloalkyladenosines with unusually high potency and selectivity for the adenosine A1 receptor. J Med Chem32:8-11 (1989) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor
Synonyms:ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptors A1
Type:Protein
Mol. Mass.:36704.13
Organism:Rattus norvegicus (rat)
Description:n/a
Residue:326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50267577
NameBDBM50267577
Synonyms:CHEMBL489640 | N6-((+/-)-endo-norborn-2-yl)adenosine
TypeSmall organic molecule
Emp. Form.C17H23N5O4
Mol. Mass.361.3956
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CC4CCC3C4)ncnc12 |r,TLB:14:15:19.18:21|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a