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Target
Mu-type opioid receptor
Ligand
BDBM50017059
Substrate
n/a
Meas. Tech.
ChEMBL_146243 (CHEMBL753435)
IC50
2±n/a nM
Citation
 Fujimoto, RA; Boxer, J; Jackson, RH; Simke, JP; Neale, RF; Snowhill, EW; Barbaz, BJ; Williams, M; Sills, MA Synthesis, opioid receptor binding profile, and antinociceptive activity of 1-azaspiro[4.5]decan-10-yl amides. J Med Chem 32:1259-65 (1989) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50017059
Synonyms:
3,4-Dibromo-N-methyl-N-(1-methyl-1-aza-spiro[4.5]dec-6-yl)-benzamide | CHEMBL279065
Type:
Small organic molecule
Emp. Form.:
C18H24Br2N2O
Mol. Mass.:
444.204
SMILES:
CN([C@H]1CCCC[C@@]11CCCN1C)C(=O)c1ccc(Br)c(Br)c1
Structure:
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