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TargetThymidine kinase, cytosolic
LigandBDBM50013119
Substrate/Competitorn/a
Meas. Tech.ChEMBL_208193
Ki 1275000±n/a nM
Citation Palomino, EMeltsner, BRKessel, DHorwitz, JP Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders. J Med Chem33:258-63 (1990) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thymidine kinase, cytosolic
Name:Thymidine kinase, cytosolic
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:25476.50
Organism:Homo sapiens (Human)
Description:ChEMBL_1333884
Residue:234
Sequence:
MSCINLPTVLPGSPSKTRGQIQVILGPMFSGKSTELMRRVRRFQIAQYKCLVIKYAKDTR
YSSSFCTHDRNTMEALPACLLRDVAQEALGVAVIGIDEGQFFPDIVEFCEAMANAGKTVI
VAALDGTFQRKPFGAILNLVPLAESVVKLTAVCMECFREAAYTKRLGTEKEVEVIGGADK
YHSVCRLCYFKKASGQPAGPDNKENCPVPGKPGEAVAARKLFAPQQILQCSPAN
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BDBM50013119
NameBDBM50013119
Synonyms:1-(5-Hydroxymethyl-tetrahydro-furan-2-yl)-4-thioxo-3,4-dihydro-1H-pyrimidin-2-one (ddUrdS) | CHEMBL89055
TypeSmall organic molecule
Emp. Form.C9H12N2O3S
Mol. Mass.228.268
SMILESOC[C@@H]1CC[C@@H](O1)n1ccc(=S)[nH]c1=O
Structure
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n/a