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Target
Beta-2 adrenergic receptor
Ligand
BDBM50010844
Substrate
n/a
Meas. Tech.
ChEBML_37835
IC50
5700±n/a nM
Citation
 Lis, R; Morgan, TK; Marisca, AJ; Gomez, RP; Lind, JM; Davey, DD; Phillips, GB; Sullivan, ME Synthesis of novel (aryloxy)propanolamines and related compounds possessing both class II and class III antiarrhythmic activity. J Med Chem 33:2883-91 (1990) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2_CANLF
Type:
PROTEIN
Mol. Mass.:
46593.67
Organism:
Canis familiaris
Description:
ChEMBL_56504
Residue:
415
Sequence:
MGQPANRSVFLLAPNGSHAPDQGDSQERSEAWVVGMGIVMSLIVLAIVFGNVLVITAIARFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAKETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAQRQLQKIDRSEGRFHAQNLSQVEQDGRSGHGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSNNSNSRSDYAGEHSGCHLGQEKDSELLCEDPPGTEDRQGTVPSDSVDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM50010844
Synonyms:
CHEMBL316868 | N-[4-(1-Hydroxy-2-{2-[4-(3H-imidazol-1-yl)-phenoxy]-ethylamino}-ethyl)-phenyl]-methanesulfonamide
Type:
Small organic molecule
Emp. Form.:
C20H24N4O4S
Mol. Mass.:
416.494
SMILES:
CS(=O)(=O)Nc1ccc(cc1)C(O)CNCCOc1ccc(cc1)-n1ccnc1
Structure:
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