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Target
D(1) dopamine receptor
Ligand
BDBM82247
Substrate
n/a
Meas. Tech.
ChEBML_31418
Ki
1.3±n/a nM
Citation
 Michaelides, MR; Schoenleber, R; Thomas, S; Yamamoto, DM; Britton, DR; MacKenzie, R; Kebabian, JW Synthesis and pharmacological evaluation of 1-(aminomethyl)-3,4-dihydro-5-hydroxy-1H-2-benzopyrans as dopamine D1 selective ligands. J Med Chem 34:2946-53 (1991) [PubMed]  Article 
Target
Name:
D(1) dopamine receptor
Synonyms:
D(1) dopamine receptor | DRD1_CARAU | Dopamine D1 receptor
Type:
n/a
Mol. Mass.:
40664.04
Organism:
Carassius auratus
Description:
n/a
Residue:
363
Sequence:
MAVLDLNLTTVIDSGFMESDRSVRVLTGCFLSVLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVTEVAGFWPFGAFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISGAWTLSVLISFIPVQLKWHKAQPIGFLEVNASRRDLPTDNCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAQIRHDSMGSGSNMDLESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSNGLPCISPTTFDVFVWFGWANSSLNPIIYAFNADFRRAFAILLGCQRLCPGSISMETPSLNKN
  
Inhibitor
Name:
BDBM82247
Synonyms:
8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SCH 23390) | CAS_87134-87-0 | CHEMBL2158641 | CHEMBL62 | SCH 23388 | SCH 23390 | SCH 23390 (R-enantiomer) | SCH 23390,R(+)
Type:
Small organic molecule
Emp. Form.:
C17H18ClNO
Mol. Mass.:
287.784
SMILES:
CN1CCc2cc(Cl)c(O)cc2[C@H](C1)c1ccccc1 |r|
Structure:
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