Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50368159
Substrate
n/a
Meas. Tech.
ChEMBL_29308 (CHEMBL640369)
Ki
1.4±n/a nM
Citation
 Thompson, RD; Secunda, S; Daly, JW; Olsson, RA Activity of N6-substituted 2-chloroadenosines at A1 and A2 adenosine receptors. J Med Chem 34:3388-90 (1992) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50368159
Synonyms:
CHEMBL315056 | CHEMBL610402
Type:
Small organic molecule
Emp. Form.:
C19H22ClN5O4
Mol. Mass.:
419.862
SMILES:
C[C@H](Cc1ccccc1)Nc1nc(Cl)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Structure:
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