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Target
D(2) dopamine receptor
Ligand
BDBM50007491
Substrate
n/a
Meas. Tech.
ChEMBL_58709 (CHEMBL669055)
IC50
>20000±n/a nM
Citation
 Hrib, NJ; Jurcak, JG; Huger, FP; Errico, CL; Dunn, RW Synthesis and biological evaluation of a series of substituted N-alkoxyimides and -amides as potential atypical antipsychotic agents. J Med Chem 34:1068-72 (1991) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50007491
Synonyms:
2-[3-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-propoxy]-isoindole-1,3-dione | CHEMBL10546
Type:
Small organic molecule
Emp. Form.:
C22H22N4O3S
Mol. Mass.:
422.5
SMILES:
O=C1N(OCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: