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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50368223
Substrate
n/a
Meas. Tech.
ChEBML_201270
Ki
660±n/a nM
Citation
 Glennon, RA; Smith, JD; Ismaiel, AM; el-Ashmawy, M; Battaglia, G; Fischer, JB Identification and exploitation of the sigma-opiate pharmacophore. J Med Chem 34:1094-8 (1991) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25124.85
Organism:
Homo sapiens (Human)
Description:
Q99720
Residue:
223
Sequence:
MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50368223
Synonyms:
Adiparthrol | Apetinil | ETILAMFETAMINE | Ethylamphetamine | N-Ethylamphetamine
Type:
Small organic molecule
Emp. Form.:
C11H17N
Mol. Mass.:
163.2594
SMILES:
CCN[C@H](C)Cc1ccccc1 |r|
Structure:
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