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TargetLysosomal phospholipase A1
LigandBDBM50368267
Substrate/Competitorn/a
Meas. Tech.ChEMBL_100184
IC50 110000±n/a nM
Citation Van Schepdael, ABusson, RVanderhaeghe, HJClaes, PJVerbist, LMingeot-Leclercq, MPBrasseur, RTulkens, PM New derivatives of kanamycin B obtained by combined modifications in positions 1 and 6". Synthesis, microbiological properties, and in vitro and computer-aided toxicological evaluation. J Med Chem34:1483-92 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lysosomal phospholipase A1
Name:Acyl-protein thioesterase 1/2
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:24708.49
Organism:Rattus norvegicus
Description:ChEMBL_100186
Residue:230
Sequence:
MCGNNMSAPMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIKSSHIKYICPHAPVMP
VTLNMSMMMPSWFDIIGLSPDSQEDESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQ
GGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLM
FGSLTVERLKGLVNPANVTFKVYEGMMHSSCQQEMMDVKYFIDKLLPPID
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50368267
NameBDBM50368267
Synonyms:KANAMYCIN B | Kanamycin | Kantrex | Klebcil
TypeSmall organic molecule
Emp. Form.C18H37N5O10
Mol. Mass.483.5139
SMILESNC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)[C@@H](O)[C@@H]1O |r|
Structure
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n/a