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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50009260
Substrate
n/a
Meas. Tech.
ChEMBL_159774 (CHEMBL763099)
IC50
0.780000±n/a nM
Citation
 Huff, JR HIV protease: a novel chemotherapeutic target for AIDS. J Med Chem 34:2305-14 (1991) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50009260
Synonyms:
1N-[4-amino(imino)methylamino-1-carbamoylbutyl]-2-(1-{2-[1-(2-hydroxy-1-methylcarboxamidopropylcarboxamido)-2-methylbutylcarboxamido]hexylamino}pentylcarboxamido)pentanediamide | CHEMBL73875
Type:
Small organic molecule
Emp. Form.:
C35H67N11O8
Mol. Mass.:
769.9754
SMILES:
CCCC[C@H](CN[C@H](CCCC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)[C@@H](C)O)[C@@H](C)CC
Structure:
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