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Reaction Details
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TargetPlatelet activating factor receptor
LigandBDBM50003510
Substrate/Competitorn/a
Meas. Tech.ChEBML_154975
IC50 21±n/a nM
Citation Carceller, EAlmansa, CMerlos, MGiral, MBartrolí, JGarcía-Rafanell, JForn, J (Pyridylcyanomethyl)piperazines as orally active PAF antagonists. J Med Chem35:4118-34 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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BDBM50003510
NameBDBM50003510
Synonyms:CHEMBL103753 | [4-(3-Hydroxy-3,3-diphenyl-propionyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile | [4-(3-Hydroxy-3,3-diphenyl-propionyl)-piperazin-1-yl]-pyridin-3-yl-acetonitrile; hydrate
TypeSmall organic molecule
Emp. Form.C26H26N4O2
Mol. Mass.426.5102
SMILESOC(CC(=O)N1CCN(CC1)C(C#N)c1cccnc1)(c1ccccc1)c1ccccc1
Structure
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n/a