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Target
Platelet-activating factor receptor
Ligand
BDBM50003526
Substrate
n/a
Meas. Tech.
ChEBML_154975
IC50
240±n/a nM
Citation
 Carceller, E; Almansa, C; Merlos, M; Giral, M; Bartrolí, J; García-Rafanell, J; Forn, J (Pyridylcyanomethyl)piperazines as orally active PAF antagonists. J Med Chem 35:4118-34 (1992) [PubMed]  Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF-R | PTAFR | PTAFR_CAVPO | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Protein
Mol. Mass.:
39005.63
Organism:
Cavia porcellus
Description:
n/a
Residue:
342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLTVADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVKYPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKGSKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAVFVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
  
Inhibitor
Name:
BDBM50003526
Synonyms:
2-[4-(Cyano-pyridin-3-yl-methyl)-piperazin-1-yl]-N-(3,3-diphenyl-propyl)-acetamide; hydrate | CHEMBL130034
Type:
Small organic molecule
Emp. Form.:
C28H31N5O
Mol. Mass.:
453.5786
SMILES:
O=C(CN1CCN(CC1)C(C#N)c1cccnc1)NCCC(c1ccccc1)c1ccccc1
Structure:
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