Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPlatelet activating factor receptor
LigandBDBM50003511
Substrate/Competitorn/a
Meas. Tech.ChEBML_154975
IC50 240±n/a nM
Citation Carceller, EAlmansa, CMerlos, MGiral, MBartrolí, JGarcía-Rafanell, JForn, J (Pyridylcyanomethyl)piperazines as orally active PAF antagonists. J Med Chem35:4118-34 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50003511
NameBDBM50003511
Synonyms:(4-{2-[Methyl-(1-phenyl-ethyl)-amino]-acetyl}-piperazin-1-yl)-pyridin-3-yl-acetonitrile; trihydrochloride; hydrate | CHEMBL545306
TypeSmall organic molecule
Emp. Form.C22H27N5O
Mol. Mass.377.4827
SMILESCC(N(C)CC(=O)N1CCN(CC1)C(C#N)c1cccnc1)c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a