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Reaction Details
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TargetPlatelet activating factor receptor
LigandBDBM50003485
Substrate/Competitorn/a
Meas. Tech.ChEBML_154975
IC50 26±n/a nM
Citation Carceller, EAlmansa, CMerlos, MGiral, MBartrolí, JGarcía-Rafanell, JForn, J (Pyridylcyanomethyl)piperazines as orally active PAF antagonists. J Med Chem35:4118-34 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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  Blast E-value cutoff:
BDBM50003485
NameBDBM50003485
Synonyms:CHEMBL134143 | [1-(3,3-Diphenyl-propionyl)-piperidin-4-ylidene]-pyridin-3-yl-acetonitrile; hydrate
TypeSmall organic molecule
Emp. Form.C27H25N3O
Mol. Mass.407.5069
SMILESO=[#6](-[#6]-[#6](-c1ccccc1)-c1ccccc1)-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\C#N)-c1cccnc1
Structure
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n/a