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Reaction Details
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TargetPlatelet activating factor receptor
LigandBDBM50003476
Substrate/Competitorn/a
Meas. Tech.ChEBML_154975
IC50 2300±n/a nM
Citation Carceller, EAlmansa, CMerlos, MGiral, MBartrolí, JGarcía-Rafanell, JForn, J (Pyridylcyanomethyl)piperazines as orally active PAF antagonists. J Med Chem35:4118-34 (1992) [PubMed]  Article
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Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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BDBM50003476
NameBDBM50003476
Synonyms:3-(4-Diphenylacetyl-piperazin-1-yl)-2-pyridin-3-yl-propionitrile; hydrate | CHEMBL132824
TypeSmall organic molecule
Emp. Form.C26H26N4O
Mol. Mass.410.5108
SMILESO=C(C(c1ccccc1)c1ccccc1)N1CCN(CC(C#N)c2cccnc2)CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a