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Reaction Details
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TargetPlatelet activating factor receptor
LigandBDBM50003554
Substrate/Competitorn/a
Meas. Tech.ChEBML_154975
IC50 2600±n/a nM
Citation Carceller, EAlmansa, CMerlos, MGiral, MBartrolí, JGarcía-Rafanell, JForn, J (Pyridylcyanomethyl)piperazines as orally active PAF antagonists. J Med Chem35:4118-34 (1992) [PubMed]  Article
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Platelet activating factor receptor
Name:Platelet activating factor receptor
Synonyms:PAF-R | Platelet-activating factor receptor
Type:Protein
Mol. Mass.:39005.63
Organism:Cavia porcellus
Description:n/a
Residue:342
Sequence:
MELNSSSRVDSEFRYTLFPIVYSIIFVLGIIANGYVLWVFARLYPSKKLNEIKIFMVNLT
VADLLFLITLPLWIVYYSNQGNWFLPKFLCNLAGCLFFINTYCSVAFLGVITYNRFQAVK
YPIKTAQATTRKRGIALSLVIWVAIVAAASYFLVMDSTNVVSNKAGSGNITRCFEHYEKG
SKPVLIIHICIVLGFFIVFLLILFCNLVIIHTLLRQPVKQQRNAEVRRRALWMVCTVLAV
FVICFVPHHMVQLPWTLAELGMWPSSNHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLSEKLNIMRSSQKCSRVTTDTGTEMAIPINHTPVNPIKN
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BDBM50003554
NameBDBM50003554
Synonyms:CHEMBL540829 | {4-[2-(Naphthalen-1-ylamino)-acetyl]-piperazin-1-yl}-pyridin-3-yl-acetonitrile; trihydrochloride
TypeSmall organic molecule
Emp. Form.C23H23N5O
Mol. Mass.385.4616
SMILESO=C(CNc1cccc2ccccc12)N1CCN(CC1)C(C#N)c1cccnc1
Structure
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n/a