Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50455778
Substrate
n/a
Meas. Tech.
ChEMBL_29305 (CHEMBL640366)
Ki
0.940000±n/a nM
Citation
 Jacobson, KA; van Galen, PJ; Williams, M Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. J Med Chem 35:407-22 (1992) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50455778
Synonyms:
CHEMBL2368675
Type:
Small organic molecule
Emp. Form.:
C19H22IN5O5
Mol. Mass.:
527.313
SMILES:
C[C@H](Cc1ccc(O)c(I)c1)Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |r|
Structure:
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