Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50008413
Substrate
n/a
Meas. Tech.
ChEBML_29305
Ki
6.9±n/a nM
Citation
 Jacobson, KA; van Galen, PJ; Williams, M Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. J Med Chem 35:407-22 (1992) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50008413
Synonyms:
8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione | 8-(1-Methyl-2-phenyl-ethyl)-1,3-dipropyl-3,9-dihydro-purine-2,6-dione | CHEMBL262984
Type:
Small organic molecule
Emp. Form.:
C20H26N4O2
Mol. Mass.:
354.446
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)[C@H](C)Cc1ccccc1
Structure:
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