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Target
Aminopeptidase N
Ligand
BDBM50001950
Substrate
n/a
Meas. Tech.
ChEBML_35366
IC50
7000±n/a nM
Citation
 Herranz, R; Vinuesa, S; Pérez, C; García-López, MT; López, E; de Ceballos, ML; Del Río, J Analgesic dipeptide derivatives. 7. 3,7-Diamino-2-hydroxyheptanoic acid (DAHHA) containing dipeptide analogues of the analgesic compound H-Lys-Trp(Nps)-OMe. J Med Chem 35:889-95 (1992) [PubMed]  Article 
Target
Name:
Aminopeptidase N
Synonyms:
AMPN_RAT | Anpep
Type:
PROTEIN
Mol. Mass.:
109431.53
Organism:
Rattus norvegicus
Description:
ChEMBL_35366
Residue:
965
Sequence:
MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSAIAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIPDSYQVTLRPYLTPNEQGLYIFKGSSTVRFTCNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPNIDTTELVERTEYLVVHLQGSLVKGHQYEMDSEFQGELADDLAGFYRSEYMEGGNKKVVATTQMQAADARKSFPCFDEPAMKASFNITLIHPNNLTALSNMLPKDSRTLQEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVSPNRVQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTAYPLEKSDQIALPDFNAGAMENWGLVTYRESALVFDPQSSSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEFLGADYAEPTWNLKDLIVLNDVYRVMAVDALASSHPLSSPANEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHTFQYSNTIYLDLWEHLQQAVDSQTAIKLPASVSTIMDRWILQMGFPVITVNTSTGEIYQEHFLLDPTSKPTRPSDFNYLWIVPIPYLKNGKEDHYWLETEKNQSAEFQTSSNEWLLLNINVTGYYQVNYDENNWRKIQNQLQTDLSVIPVINRAQIIHDSFNLASAGKLSITLPLSNTLFLASETEYMPWEAALSSLNYFKLMFDRSEVYGPMKRYLKKQVTPLFAYFKIKTNNWLDRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWMNNSDNNPIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRKATLVNEADKLRSALACSNEVWILNRYLSYTLNPDYIRKQDATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKEDNSATGFGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS
  
Inhibitor
Name:
BDBM50001950
Synonyms:
2-(3,7-Diamino-2-hydroxy-heptanoylamino)-3-[2-(2-nitro-phenylsulfanyl)-1H-indol-3-yl]-propionic acid methyl ester | CHEMBL354438
Type:
Small organic molecule
Emp. Form.:
C25H31N5O6S
Mol. Mass.:
529.609
SMILES:
COC(=O)[C@H](Cc1c(Sc2ccccc2[N+]([O-])=O)[nH]c2ccccc12)NC(=O)[C@@H](O)[C@H](N)CCCCN
Structure:
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