Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50005366
Substrate
n/a
Meas. Tech.
ChEMBL_29001 (CHEMBL643476)
Ki
16±n/a nM
Citation
 Shimada, J; Suzuki, F; Nonaka, H; Ishii, A 8-Polycycloalkyl-1,3-dipropylxanthines as potent and selective antagonists for A1-adenosine receptors. J Med Chem 35:924-30 (1992) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50005366
Synonyms:
1,3-Dipropyl-8-thiophen-2-yl-3,7-dihydro-purine-2,6-dione | CHEMBL33722
Type:
Small organic molecule
Emp. Form.:
C15H18N4O2S
Mol. Mass.:
318.394
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1cccs1
Structure:
Search PDB for entries with ligand similarity: