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TargetHuman immunodeficiency virus type 1 protease
LigandBDBM50407048
Substrate/Competitorn/a
Meas. Tech.ChEMBL_159480
IC50 27±n/a nM
Citation Tam, TFCarrière, JMacDonald, DCastelhano, ALPliura, DHDewdney, NJThomas, EMBach, CBarnett, JChan, H Intriguing structure-activity relations underlie the potent inhibition of HIV protease by norstatine-based peptides. J Med Chem35:1318-20 (1992) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Human immunodeficiency virus type 1 protease
Name:Human immunodeficiency virus type 1 protease
Synonyms:Pol polyprotein
Type:Enzyme Subunit
Mol. Mass.:10781.16
Organism:Human immunodeficiency virus type 1
Description:n/a
Residue:99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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BDBM50407048
NameBDBM50407048
Synonyms:CHEMBL3085513
TypeSmall organic molecule
Emp. Form.C38H48N6O6
Mol. Mass.684.8243
SMILES[H][C@@]12CCCC[C@]1([H])CN([C@@H](C2)C(=O)NC(C)(C)C)C(=O)[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc2ccccc2n1
Structure
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